Research Interests: Equine orthopaedic surgery, joint disease research as well as osteoarthritis therapy (including gene therapy and stem cell therapies), articular cartilage repair, and early diagnosis in osteoarthritis and pre-fracture disease using imaging and fluid biomarkers.
Dr. McIlwraith, a University Distinguished Professor, has made significant strides in advancing the Orthopaedic Research Center Laboratory's reputation through publications, scientific presentations, and fundraising. He is a Past-President of the American College of Veterinary Surgeons and the American Association of Equine Practitioners, and a recognized leader in the field of equine orthopaedic research and surgery. He consults worldwide as a specialist equine surgeon and has received media attention for his contributions to joint research. Dr. McIlwraith is the co-author of five textbooks, over 400 textbook chapters and refereed publications, and has given 600 presentations and workshops.
BVSc, Massey University (N.Z.), 1970Dip. Surgery, University of Guelph, Cananda, 1975MS, Purdue University, 1977PhD, Purdue University, 1979Dr. Med. Vet (honoris causa), University of Vienna, 1995D.Sc., Purdue University, 2001D.Sc. (honoris causa), Massey University, 2003Laurea Dr. (honoris causa), University of Turin, 2004Dr. Vet. Med. (honoris causa), Royal Veterinary College, University of London, 2010
American College of Veterinary Surgeons, 1979Diplomate
European College of Veterinary Surgeons, 1994Diplomate
American College of Veterinary Sports Medicine and Rehabilitation, 2010
(selected from 322 entries)Ferris DJ, Frisbie DD, McIlwraith CW, Kawcak CE. Current joint therapy usage in equine practice: A survey of veterinarians 2009. Equine Vet J 2011;43:530-535. doi: 10.1111/j.2042-3306.2010.00324.x. Kawcak CE, McIlwraith CW. Comparison of synovial fluid in middle carpal joints undergoing needle aspiration, infusion with saline, and infusion with a combination of n-acetyl-D-glucosamine, hyaluronic acid and sodium chondroitin sulfate. J Equine Vet Sci 2011;31:155-159.Maher MC, Werpy NM, Goodrich LR, McIlwraith CW. Positive contrast magnetic resonance bursography for assessment of the navicular bursa and surrounding soft tissues. Vet Radiol Ultrasound 2011;52:385-393. doi: 10.1111/j.1740-8261.2011.01810.x.McIlwraith CW, Frisbie DD, Rodkey WG, Kisiday JD, Werpy NM, Kawcak CE, Steadman JR. Evaluation of intra-articular mesenchymal stem cells to augment healing of microfractured chondral defects. Arthroscopy 2011;27:1552-61.McIlwraith CW, Fortier LA, Frisbie DD, Nixon AJ. Equine models of articular cartilage repair. Cartilage 2011;2:317-326.Kisiday JD, Hale BW, Almodovar JL, Lee CM, Kipper MJ, McIlwraith CW, Frisbie DD. Expansion of mesenchymal stem cells on fibrinogen-rich protein surfaces derived from blood plasma. J Tissue Eng Regen Med 2011;5:600-611. doi:10.1002/term.352.Firth EC, Rogers CW, van Weeren PR, Barneveld A, McIlwraith CW, Kawcak CE, Goodship AE, Smith RK. Mild exercise early in life produces changes in bone size and strength but not density in proximal phalangeal, third metacarpal and third carpal bone of foals. Vet J 2011;190:383-389. doi:10.1016/j.tvjl.2010.11.016.Smith RK, McIlwraith CW. Consensus on equine tendon disease: building on the 2007 Havemeyer symposium. Equine Vet J 2012;44:2-6. doi:10.1111/j.2042-3306.2011.00497.x.Ferris DJ, Frisbie DD, Kisiday JD, McIlwraith CW. In vivo healing of meniscal lacerations using bone marrow derived mesenchymal stem cells and fibrin glue. Stem Cell International 2012;2012:691605.Henson FM, Getgood AM, Caborn DM, McIlwraith CW, Rushton N. Effect of a solution of hyaluronic acid-chondroitin sulfate-N-acetyl glucosamine on the repair response of cartilage to single-impact load damage. Am J Vet Res 2012;73:306-312.Contino EK, Park RD, McIlwraith CW. Prevalence of radiographic changes in yearling and 2-year-old Quarter Horses intended for cutting. Equine Vet J 2012;44:185-195. doi: 10.1111/j.2042-3306.2011.00432.xHale BW, Goodrich LR, Frisbie DD, McIlwraith CW, Kisiday JD. Effect of scaffold dilution on migration of mesenchymal stem cells from fibrin hydrogels. Am J Vet Res 2012;73:313-318.Corbin LJ, Blott SC, Swinburne JE, Sibbons C, Fox-Clipsham LY, Helwegen M, Parkin TD, Newton JR, Bramlage LR, McIlwraith CW, Bishop SC, Woolliams JA, Vaudin M. A genome-wide association study of osteochondritis dissecans in the Thoroughbred. Mamm Genome 2012;23:294-303.Barrett MF, Frisbie DD, McIlwraith CW, Werpy NM. The arthroscopic and ultrasonographic boundaries of the equine femorotibial joints. Equine Vet J 2012;44:57-63. doi: 10.1111/j.2042-3306.2011.00396.x.Firth EC, Rogers CW, van Weeren PR, Barneveld A, McIlwraith CW, Kawcak CE, Goodship AE, Smith RKW. The effect of previous conditioning exercise on diaphyseal and metaphyseal bone to imposition and withdrawal of training in young Thoroughbred horses. Vet J 2012;192:34-40. doi:10.1016/j.tvjl.2011.05.016.Kim W, Kawcak CE, McIlwraith CW, Firth EC, Broom ND. Histologic and histomorphometric evaluation of midcarpal joint defects in Thoroughbreds raised with and without early exercise. Am J Vet Res 2012;73:498-507.McIlwraith CW, Frisbie DD, Kawcak CE. Evaluation of intramuscularly administered sodium pentosan polysulfate for treatment of experimentally induced osteoarthritis in horses. Am J Vet Res 2012;73:628-633.Southwood LL, Kawcak CE, Hidaka C, McIlwraith CW, Werpy N, Macleay J, Frisbie DD. Evaluation of direct in vivo gene transfer in an equine metacarpal IV ostectomy model using an adenoviral vector encoding the bone morphogenetic protein-2 and protein-7 gene. Vet Surg 2012;41:345-354.Fortier LA, Cole BJ, McIlwraith CW. Science and animal models of marrow stimulation for cartilage repair. J Knee Surg 2012;25:3-8.Antonacci JM, Schmidt TA, Serventi LA, Cai MZ, Shu YYL, Schumacher BL, McIlwraith CW, Sah RL. Effects of equine joint injury on boundary lubrication of articular cartilage by synovial fluid: role of hyaluronan. Arthritis Rheum 2012. doi: 10.1002/art.34520.Kisiday JD, McIlwraith CW, Rodkey WR, Frisbie DD, Steadman JR. Effects of platelet-rich plasma composition on anabolic and catabolic activities in equine cartilage and meniscal explants. Cartilage 2012. doi: 10.1177/1947603511433181.